Welcome to the next issue of Clinical Insights in Eyecare for 2025.
This edition features a timely Point-Counterpoint debate, 4 insightful case reports, and our ever-valuable journal scans that summarize key updates from recent literature.
Our lead case report for this issue is “Combined Central Retinal Vein and Cilioretinal Artery Occlusion: A Case Report and Review,” by Jaymeni Patel, OD, FAAO. This striking presentation of simultaneous venous and arterial occlusion provides an important reminder that mixed vascular events, though rare, require rapid recognition and coordinated management. Dr Patel’s review of underlying pathophysiology and evidence-based treatment options offers practical guidance for clinicians encountering similar high-risk vascular emergencies.
In “Presumed Iatrogenic Optic Neuropathy Secondary to Nivolumab Therapy for Advanced Melanoma,” Lindsay B. Howse, OD, FAAO, highlights the potential neuroophthalmic complications of immune checkpoint inhibitors. The report emphasizes the importance of vigilant monitoring and interdisciplinary communication when managing patients receiving systemic immunotherapy.
Our next case report, “Diagnosis and Management of Phacolytic Glaucoma,” by Harneet Randhawa, OD, FAAO, presents a clear and efficient overview of this acute secondary glaucoma. The case reinforces the need for prompt identification, immediate intraocular pressure control, and expedited cataract extraction to safeguard long-term vision.
This issue also includes a valuable case series authored by Paula McDowell, OD, FAAO; Avesh Raghunandan, OD, PhD, FAAO; Sophia Capo, OD, FAAO; and Corrie Anderson, OD. Their work on amblyopia management in cases with concurrent foveal hypoplasia provides thoughtful clinical insights into tailoring treatment strategies when structural anomalies complicate prognostic expectations.
Our Point-Counterpoint this quarter focuses on pediatric care, presenting a balanced discussion on tropicamide vs cyclopentolate for cycloplegic refractions in children. The authors explore diagnostic accuracy, pharmacologic profiles, and real-world considerations that will help clinicians refine their approach to pediatric refractions.
As always, Drew Rixon, OD, FAAO, and Eddie Chu, OD, FAAO, contribute insightful journal scans with practical takeaways from recent studies.
We hope you find this issue thoughtful, clinically meaningful, and engaging.
Raman Bhakhri, OD, FAAO
Editor in Chief
Jim Williamson, OD, FAAO
Associate Editor